Friday, November 30, 2012

U.N. Agency Says 2012 Ranks Among Hottest Years

GENEVA ? This year has ranked among the nine warmest since records began more than 160 years ago, continuing a trend for the planet that is increasing the dangers of extreme weather events, according to United Nations meteorologists.

?It confirms the trend towards a warmer planet,? Michel Jarraud, head of the World Meteorological Organization at the United Nations, said in Geneva on Wednesday as he delivered a provisional assessment intended to inform policy makers and negotiators attending the U.N. Climate Change Conference in Doha, Qatar.

The final judgment on 2012 will come in March, but Mr. Jarraud said that meteorologists were not observing any major events that would greatly alter the preliminary findings.

?Climate change is taking place before our eyes and will continue to do so as a result of concentrations of greenhouse gases in the atmosphere, which have risen constantly and again reached new records,? he added in a prepared statement.

Among the most conspicuous evidence of climate change associated with global warming was the ?alarming? rate at which Arctic ice had melted during the summer months, he said. The melting this year occurred at a much faster rate than in 2011 and outpaced the predictions of climate experts on the Intergovernmental Panel on Climate Change, he said.

By September, the level of Arctic ice was the lowest since satellite records began and had shrunk by nearly half ? an area nearly the size of India ? below the average minimum level in the 20 years before 2000, the organization reported.

The ice will reform in the winter but will be thinner than before and more vulnerable to further melting, Mr. Jarraud warned. ?The trend is not only continuing but accelerating,? he said. ?The more it melts, the faster it will melt.?

The ice melt will contribute to rising sea levels that are already 20 centimeters, or nearly 8 inches, higher than a century ago, Mr. Jarraud said, posing added risks in the event of extreme weather. Hurricane Sandy would have had less impact on New York if it had occurred 100 years ago when sea levels were lower, he said.

After a chilly start to 2012, average temperatures from January to October were 0.45 degrees Celsius, or 0.81 degrees Fahrenheit, above the average from 1961 to 1990, according to the World Meteorological Organization?s findings. A rise of only one degree Celsius was sufficient to increase the frequency of extreme weather events, Mr. Jarraud said.

The above-average temperatures experienced in 2012 had been marked by record temperatures in areas like Greenland, Siberia and central China, the World Meteorological Organization reported.

Much of the United States, together with parts of Europe, western Russia and southern China, had suffered severe drought, while parts of West and sub-Saharan Africa had experienced severe flooding.

Meteorologists have been at pains to make clear that no major weather event was the result of a single cause, but research into climate change was establishing clear links, Mr. Jarraud said, citing the results of research into the extreme heat wave in Russia in 2010. ?Without climate change, this episode would have been very unlikely,? he said.

Source: http://www.nytimes.com/2012/11/29/science/earth/un-agency-says-2012-ranks-among-hottest-years.html?partner=rss&emc=rss

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Thursday, November 29, 2012

Katy Perry gets a perfume deal

Katy Perry is adding some new scents to her perfume line.

The singer and songwriter is to develop a line of signature scents with beauty company Coty Inc., according to an announcement released Wednesday. Coty will distribute them on a larger scale than the Purr and Meow! perfumes that Perry previously crafted.

The company says Perry's "unique approach to music and life" will drive her inspiration, and move toward "new avenues of scent creation."

Other pop stars to concoct their own fragrances include Rihanna, Jennifer Lopez and Taylor Swift. Coty's perfume brands include Calvin Klein, Marc Jacobs and Playboy.

Source: http://news.yahoo.com/katy-perry-gets-perfume-deal-164617289.html

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Reds sign P Broxton to 3-year, $21 million deal

CINCINNATI (AP) ? The Reds signed Jonathan Broxton to a three-year, $21 million contract on Wednesday, giving the NL Central champions a potential closer and a chance to reconfigure their starting rotation.

Broxton came to the Reds last July in a trade with Kansas City and was part of their push toward the playoffs. He filled in as the closer when Aroldis Chapman came down with a tired shoulder and had four saves in six chances overall with a 2.82 ERA, impressing the Reds.

Now they have the option of turning Chapman into a starter, which was the plan last season until closer Ryan Madsen tore up his pitching elbow.

The Reds have told Chapman to prepare for next season as a starter, although they haven't committed to Broxton as the closer.

"Nothing's in stone right now," assistant general manager Bob Miller said. "We told (Chapman) before he left to prepare because that's the hardest part ? starter. When we talked to Jonathan we said he was going to be at the back end of the bullpen. What happens depends on spring training and how things play out in the offseason."

Broxton's deal pays him a $4 million base salary in 2013, $7 million in 2014 and $9 million in 2015. There's a club option for another year at $9 million with a $1 million buyout. He also got a limited no-trade provision. Broxton gets to pick 10 teams each year that would be acceptable in a trade. If he's dealt, the club option becomes a mutual option and the buyout increases by $1 million.

Broxton wanted a multiyear deal so he could settle in one place. He didn't insist on assurances he'd be a closer.

"I went into the offseason with an open mind," Broxton said, on a conference call. "I've got experience in both roles. Even if Chapman doesn't work out as a starter, he can come back in and fill in as the closer. I'll be happy to throw the eighth (inning). It doesn't matter to you. You saw what he did last year."

It's Cincinnati's second big decision of the offseason. The Reds also brought back manager Dusty Baker on a two-year deal. Cincinnati also would like to upgrade its leadoff spot in the batting order.

The 28-year-old Broxton missed most of the 2011 season with the Dodgers because of a bone spur in his elbow that required surgery. He agreed to a $4 million, one-year deal with Kansas City last season, starting as a setup man for closer Joakim Soria. He assumed the closing role in March, when Soria had to have reconstructive elbow surgery.

Broxton had 23 saves in 27 chances for Kansas City. He was surprised when the Reds traded for him, looking to upgrade their setup situation as they closed in on the playoffs.

Broxton's agent, B.B. Abbott, talked to several teams about a multiyear deal before deciding to stick with the Reds, who expect to be a contender. Cincinnati has won the division two of the last three years, losing in the first round of the playoffs both times.

The Reds signed Madson as their closer a year ago, giving him a one-year contract for $8.5 million. There was a mutual option for 2013 at $11 million with a $2.5 million buyout. Madson blew out his elbow during spring training and chose to become a free agent under his buyout.

The Reds planned to use Chapman as a starter last season, seeing how his 100 mph fastball fared in his more accustomed role. When Madson got hurt along with Cincinnati's two setup relievers during spring training, the Reds moved Chapman to the bullpen and Baker eased him into the closing role.

Chapman saved 27 consecutive chances and was 38 of 43 overall in save opportunities with a 1.55 ERA in 68 appearances. The Reds are hoping to give him a chance to make the rotation next season.

___

Follow Joe Kay on Twitter: http://twitter.com/apjoekay

Source: http://news.yahoo.com/reds-sign-p-broxton-3-21-million-deal-145928806--mlb.html

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Real Estate Marketing Plan ? Target the Right Audience for Your ...

real estate marketingOnce you have developed a budget and set specific goals, the next step in any real estate marketing plan is to research the desired target audiences to ensure your marketing campaigns are directed at the appropriate customers.? Knowing your target audience maximizes the return on marketing dollars and offers the best chance of generating leads or clients throughout the marketing campaign.

Use Demographics

There are several methods for determining the correct target market for any real estate marketing campaign.? One way is to use different demographics based on the market you are trying to reach.? Demographics may include age, income, geography or marital status.? Families with children will have different real estate needs than retired executives.? Lower income families do not have the same buying power as those with higher incomes.? In addition, because each demographic in your market shops in different locations and finds information about products in different ways, choosing the right marketing method is crucial to achieving success through any real estate marketing strategy.

Develop a Consumer Profile

Also helpful when determining the target audience in any real estate marketing campaign is to develop a consumer profile. Customer profiles empower you to create marketing strategies specific to the demographics you are trying to reach. Think about? the beliefs, values, emotions and lifestyle choices of the customer your real estate marketing ideas should reach. Then put together a profile of that person. For example, if you are marketing high-end condominiums, the consumer profile would include an older, wealthier consumer, possibly retired or without children, who enjoys traveling.? These consumers are more likely to purchase a condominium due to the lack of yard maintenance required.

Benefits of Marketing to Targeted Audience

By focusing a real estate marketing plan on targeted audiences, you have the opportunity to focus the advertising budget on those that are most likely to respond to the marketing campaign.? A focused campaign motivates consumers to respond as they feel the campaign is directed specifically at them.? In addition, your advertising dollars reach customers that will generate the best return on your advertising investment.

Knowing your target audience is crucial to your real estate marketing plan in order to get the most out of your advertising budget and to generate more leads or clients.? Visit our website for more tools and resources.

Source: http://blog.xpressdocs.com/real-estate-marketing-plan-target-the-right-audience-for-your-campaigns/

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Wednesday, November 28, 2012

jomlusingh2563: ramgopall987456ramgopall987456: Hobby Lobby


Added: 6 hours ago
via: Android Market
Category: Lifestyle
By: Hobby Lobby...
Updated: November 15, 2012
????? 60 ratings
Requires Android 2.3.3 and up

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We are not just an arts and crafts store. With over 65,000 items to explore including Home Accents, Crafts, Hobbies, Picture Framing, Jewelry Making, Fashion Fabrics, Floral, Cards & Party, Baskets, Wearable Art and Holiday Supplies, Hobby Lobby is the place to shop with super savings and super selections every day!
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What?s in this version:

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Source: http://appaggie.com/2012/11/18/hobby-lobby-stores/

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Kupambana Links the Worlds of Creativity and Communications

new foundation to sponsor arts education and research the contribution of the arts to the UK economy

Wednesday, November 28th, 2012

Kupambana, a not-for-profit foundation to champion the visual and creative arts, was launched today by Culture Secretary Maria Miller.

Its name comes from a Swahili word meaning ?to fight for what you believe in?. The foundation has a variety of goals, including:

  • Sponsoring students at graduate and post-graduate level
  • Researching the economic contribution of the creative arts
  • Comparing British creativity with that around the world
  • Broadening the link between business and academia
  • Identifying creative arts applications in communications

The Foundation will partner with academic institutions around the world and will base its research centre in London at Chelsea College of Art and Design.

Kupambana is already funding student showcases including catalogues and exhibitions. The two organisations are also partnering to develop creative education for communications professionals.

Additional partnerships will be announced in the coming months.

The goal of the Foundation is simple ? to bridge the gap between the creative arts and industry. This will push the boundaries of both sides.?

Quotes

George Blacklock, Dean of Chelsea College of Art and Design, said; ?At a time when funding for students pursuing a career in the creative arts is so challenging, the work of the Kupambana Foundation is vital. It will bring exposure and experience for some outstanding young artistic talent ? and change the way communicators use creative content.?

Rt Hon Maria Miller MP, the Secretary of State for Culture, Media and Sport said: ?I?m delighted to see this new link between arts education and the creative industries. Both are world-class and we should be proud of the contribution they make to our reputation globally.?

Chris Lewis, CEO at LEWIS PR and founder of Kupambana said, ?The communications industry is changing fast. New digital channels enable new ways of communicating. The key to success is digital content that is creative, quick, polished and timely. This is likely to come from better and more plentiful graphics, photography, illustration, and videography.

Source: http://live.lewispr.com/LEWISPR/2012/11/28/kupambana-links-the-worlds-of-creativity-and-communications-031243

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Embree suggests he would have needed shortcuts

BOULDER, Colo. (AP) ? A choked-up Jon Embree suggested Monday that the only way he could have turned around the University of Colorado's flailing football program in his two years as head coach was to take shortcuts in the classroom and on the recruiting trail.

"If you just hire the next guy and say you've got two years, keep your fingers crossed," Embree said at his farewell news conference a day after being fired.

Athletic director Mike Bohn, who fired Embree less than two years after he signed him to a five-year deal, said, "Shortcuts are not going to be an answer and we're not going to hire a coach that expects to use shortcuts."

What he does expect is a quick turnaround from a free-fall that saw the Buffaloes thumped by an average score of 48-17 in the Pac-12 during a 1-11 season that was the worst in the program's 123-year history.

In some ways, Embree's quick hook might have had a lot to do with the administration patiently sticking with his predecessor, Dan Hawkins, through five losing seasons, resulting in the proverbial bare cupboard.

Bohn bristled at that notion.

"Jon's results were extremely revealing in a very short period of time, and the prowess of the Pac-12 conference revealed it a lot faster," Bohn said.

Embree, who gets a $1.625 million buyout, suggested he got a raw deal, pointing out he only got 1? recruiting classes to turn around a program that had been down on its luck for several years.

Chancellor Philip P. DiStefano said he appreciated Embree's passion for the program but said it just wasn't working out.

"It's performance and progress. And unfortunately, this year, we didn't see either," he said.

Bohn pointed to a program that was headed in the wrong direction both on and off the field, going 4-21 under Embree, with so many blowouts leading to too many empty seats, though he insisted boosters had nothing to do with this decision.

"Our boosters' resources have never been a factor in my tenure," Bohn said. "Although the erosion of our fan base and the ticket sales certainly doesn't help."

Bohn said he had no preferred candidate in mind but acknowledged the school would have to pay more than Embree's incentive-laden deal that was worth $741,000 annually plus bonuses of up to $200,000 for reaching off-the-field goals and up to $1 million for meeting on-the-field benchmarks.

Bohn said he was still forming a search committee but wanted to make a hire as soon as possible.

Embree, a star tight end for the Buffs in the 1980s, was fired Sunday night, 48 hours after a 42-35 loss to Utah left them without a home win for the first time since 1920.

In a news conference at Folsom Field that lasted more than an hour, Embree began by addressing players who had packed the Varsity Room at the Dal Ward Center and telling them to keep up the good fight without him.

"You had the highest GPA the last three semesters that this school has ever had in the football program. You stayed out of trouble. You guys represented yourselves well," Embree said. "You set a legacy and a standard, and as I told you guys when we're going through tough times, you're not judged by the scoreboard at the end of the day.

"I was. But you won't be."

Even though he'd been stripped of his powers, Embree was still coaching his kids, using the first seven minutes of the news conference to speak directly to them.

Asked if the next coach can win in Boulder, Embree retorted, "How long does he have?"

Embree embraced dozens of his players on his way out of the room and was followed at the microphone by Bohn and DiStefano with university President Bruce Benson listening in on speaker phone while on vacation.

"Jon is a dedicated alum of the university and the Colorado Buffaloes with a passion for his students and the athletic program as a whole," DiStefano said. "And if this decision were based on passion for CU and dedication, there's no doubt that Jon would be coach for life.

"But it also has to be based on progress and results, which we simply did not see enough this year," DiStefano continued. "And so we looked at the performance on the field and did not see the development and the cohesion nor progressive strategy that gave us confidence in the future, and that's why this decision was made."

Embree said six of his coaches offered to resign in order for him to keep his job.

He said he was disappointed because had been given assurances when he was hired that he'd be given the time needed to turn around a downtrodden program. He said that support changed suddenly Saturday night in a phone call with Bohn.

"All I was told (Sunday) was the trajectory of the program wasn't what they wanted. And my response was, 'Well, what was the trajectory of the program before I was hired?'" Embree said.

Defensive end Will Pericak said the players are angry over Embree's dismissal.

"Not a fair chance at all," Pericak said. "Embree needed another year, absolutely."

Most players filed out after Embree left, but kicker Will Oliver stuck around and didn't like what he heard when Bohn spoke about the importance of a third year in turning things around, a chance he didn't afford Embree.

"It seemed like a lot of political jabber," Oliver said. "I don't know what I just listened to for 30 minutes, to be completely honest. He might figure this out. I guess we'll find out soon."

Embree had just eight seniors on this year's team, and in addition to a staff makeover, he was planning to switch to a spread offense and tweak his defense next year.

"We went up against some really good teams that we weren't quite able to match up with," Embree said. "And some of it was just physical differences. We were young. Some of it, we had injuries. But at the end of the day, there was never any quit. They fought to the last play. They did a good job of not looking at the scoreboard."

The administration, though, sure did.

___

AP freelancer Monica Costello contributed.

___

Follow Arnie Melendrez Stapleton on Twitter: http://twitter.com/arniestapleton

Source: http://news.yahoo.com/embree-suggests-needed-shortcuts-233654251--spt.html

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Tuesday, November 27, 2012

Family Friendly Christmas Party Ideas ? Celebrations at Home

I?m excited to finally share this project I worked on with Urbanity Studios. I spoke with them several months ago about styling a party around one of their invitations, but they also wanted to highlight the fact that they can customize them through colors and wording, and offer coordinating pieces as well. I decided to style the same basic party in 3 different color schemes and I?ll be sharing each one separately.

Today is our traditional color palette of red and green, but our decorative details are whimsical and playful for a Family Friendly Christmas party. Read on for the details, and to get your FREE downloadable tags that match this set?

Get the Look:

  • This entire party was inspired by the patchwork Christmas tree invitation with it?s whimsical tree and string of ornaments graphic. Send out invitations soon, and use their coordinating address label wraps for a completed look.
  • Since ?whimsy? is the word of the day, I used dots and stripes throughout the decor. It doesn?t get more whimsical than dots! This also appeals to our younger guests at this family party.
  • White fudge dipped Oreos are dressed up with decorations from the baking aisle ? a simple trick anyone can do, and get that ?designer? look.
  • Urbanity Studios can provide coordinating signs & menus for your party too. I used a small sign to frame a menu for the sweets table ? an alternative to using individual food labels.

  • This easy menu consists of cupcakes, cheesecake mousse parfaits, white dipped Oreos, white truffles, powdered donuts, and various candies. Spoons for the parfaits are dressed up with tiny Santa hats found at the craft store.
  • I made favor boxes out of large matchboxes, and wrapped them in scrapbook paper. A coordinating sticker from Urbanity Studios tops them off in style. Fill them up with small candies or a small ornament.
  • Serving a red tinted punch in an apothecary jar keeps the party?s colors uninterrupted. Just use a punch bowl ladle to scoop it up.
  • Put your Christmas packages to work for you and let them decorate your party space. Stack boxes and place them in nooks and corners to add brightness.
  • The backdrop was designed to resemble the invitation with it?s hanging ornaments. I used ornament wall clings and ?hung? them with thin ribbon. A thicker ribbon is used like a swag to frame out the entire dessert table.

This was such a fun project to work on and I can?t wait to share the other 2 party design with you. Urbanity Studios has a wonderful gift to you as well. They are offering FREE Christmas tags that coordinate with each of the 3 parties I styled.? Just use a hole punch to loop a ribbon through, and tie them on. ? Get the downloads here.

For more inspiration, follow me on Pinterest, Twitter and Facebook. Cheers!

This is a sponsored post per Celebrations At Home styling service.

Source: http://celebrationsathomeblog.com/2012/11/family-friendly-christmas-party-ideas.html

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New understanding of X chromosome inactivation

ScienceDaily (Nov. 27, 2012) ? In a paper published in the Nov. 21 issue of Cell, a team led by Mauro Calabrese, a postdoctoral fellow at the University of North Carolina in the lab of Terry Magnuson, chair of the department of genetics and member of the UNC Lineberger Comprehensive Cancer Center, broadens the understanding of how cells regulate silencing of the X chromosome in a process known as X-inactivation.

"This is a classic example of a basic research discovery. X-inactivation is a flagship model for understanding how non-coding RNAs orchestrate large-scale control of gene expression. In the simplest terms, we are trying to understand how cells regulate expression of their genes. Our findings are relevant across the board -- by understanding how normal cells function we can apply that knowledge to similar situations in the understanding and treatment of disease," said Calabrese.

Proper regulation of the X chromosome plays a crucial role in mammalian development. Females inherit a pair of X chromosomes from their parents, and the process of X-inactivation shuts down one of these two Xs.

"Males have XY. Females have two Xs. One of those Xs needs to get shut off. If it does not, it's not compatible with life. It's how we have evolved to equalize doses between males and females," said Calabrese.

While the manner in which the X chromosome is deactivated has been actively studied for 50 years, the exact mechanisms that regulate the process remain a mystery. Calabrese's research used high-throughput sequencing to determine the location and activity of chromosomes with far greater accuracy than previous research.

"Basically, this is using the sequencing technology as a high resolution microscope," said Calabrese.

Under a microscope, the inactive X chromosome (Xi) appears as a cloud-like structure, because it is covered with a non-coding RNA known as Xist. In the traditional model of X-inactivation, genes located inside the cloud are completely silenced, with 15 percent of the genes from the inactive X chromosomes escaping to become active.

"The prevailing thought was that genes that escaped X inactivation were pulled out of the core and expressed out there," said Calabrese.

The work of Calabrese's team complicates the current model of X-inactivation by finding indications of gene activity inside the Xist cloud and the presence of inactive genes outside the cloud, both of which would not have been thought possible in the prevailing model.

"It's kind of a subtle thing, but mechanistically it is a big difference," said Calabrese.

Inside the Xist cloud, sequencing discovered traces of DNase I sensitivity, a feature usually linked to transcription activity. While other markers associated with transcription were absent, the presence of DNase I sensitivity suggested that the nucleus did recognize the inactive X as usable DNA, but an unknown suppressive mechanism was preventing genes from being activated.

"We were surprised to see that. If they were totally silent, you would expect this to be not there? This suggests that transcription factors or other proteins that bind DNA are still accessing the inactive X," said Calabrese.

The other surprising findings involve the 15 percent of "escaper" genes from the inactive X. Calabrese found evidence that active genes were found both inside and outside the Xist cloud, and that silenced genes that lay alongside active genes outside of the Xist cloud remained inactive.

"If X-inactivation was a strict nuclear barrier, then pulling a gene outside the barrier would turn it on, but it has got to be more than that because when an inactivated gene that is beside an escaper is outside this domain, it is still turned off," said Calabrese.

The presence of DNase I sensitivity within the Xist cloud and the finding of inactive genes outside of the cloud suggest that a site-specific mechanism is regulating genes on the chromosome in a more subtle way than the binary "on/off" function posited by the prevailing model. The exact mechanism for this remains unknown. Although Calabrese believes that Xist still plays a role, its exact function and whether other factors influence X-inactivation remain questions for future research.

"We know that Xist is required to turn off the inactive X. We know that. We have no idea how" said Calabrese.

Beyond revising the understanding of how X-inactivation works, Calabrese said that deeper understanding of the function of Xist could reveal more about the role of other non-coding RNAs in cellular development. These RNAs could become useful targets for future therapies and drug development.

"We know that too much expression of the wrong non-coding RNAs can lead to cancer. Also, forced expression of other non-coding RNAs can prevent cancer. Generally, we do not know how these RNAs work," said Calabrese.

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Story Source:

The above story is reprinted from materials provided by University of North Carolina Health Care. The original article was written by Mary Ruth.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. J.?Mauro Calabrese, Wei Sun, Lingyun Song, Joshua?W. Mugford, Lucy Williams, Della Yee, Joshua Starmer, Piotr Mieczkowski, Gregory?E. Crawford, Terry Magnuson. Site-Specific Silencing of Regulatory Elements as a Mechanism of X Inactivation. Cell, 2012; 151 (5): 951 DOI: 10.1016/j.cell.2012.10.037

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/r29Zybqw_qY/121127101534.htm

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Illuminating the no-man's land of waters' surface: Strong electric charge observed at the interface between oil and water is not due to impurities

ScienceDaily (Nov. 27, 2012) ? Water repelling molecules are said to be hydrophobic. The hydration -- or formation of water interfaces around hydrophobic molecules -- is important for many biological processes: protein folding, membrane formation, transport of proteins across an interface, the transmission of action potentials across membranes. It is involved as well in the process of creating mayonnaise, or in the fact that you can get rid of fat with soap. Hydrophobic interfaces although long studied, are poorly understood.

Here's an amusing kitchen-table experiment to illustrate waters unusual properties: put a drop of pure insulating oil in a glass of pure, non-conducting water, and create an electric field using two wires hooked up to a battery. You'll see the oil move from the negative to the positive pole of the little circuit you've created. You have created charge in a mixture that was neutral, and a huge amount of it too, judging from the speed at which the droplets move. The same thing happens for gas bubbles in water; the phenomenon of charging applies to all hydrophobic/water interfaces.

A century of debates

It's not a new discovery; scientists have observed the phenomenon in the middle of the 19th century. But despite more than a century of research, the reason why such a huge electric charge exists is still the subject of heated debate.

In an article published this week in Angewandte Chemie -- a journal of reference in the field -- EPFL scientist Sylvie Roke challenges a hypothesis put forward last spring in the same journal. With experimental proof to back her up, the holder of the Julia Jacobi chair in photomedicine makes her case: the phenomenon is not caused by the inevitable "impurities" present in oils, as her colleagues claim, but rather by certain intrinsic properties of the water molecules involved.

Show the unseeable

For proof, Roke turns to the technologies in which she is an expert -- nonlinear optics and light diffusion. Using carefully filtered lasers channeled through a complex circuit of mirrors and lenses, she "hits" her sample -- barely a drop -- and measures the wavelength of the light that escapes from it. With this she can detect whether or not there are nanoscopic molecules on the interface between the oil and the water.

The precision of the observations "shows that negative charges exist even in a total absence of surface impurities, and thus the explanation put forward by my colleagues, which was derived from charge measurements and chemical titrations of the bulk liquids, doesn't hold up," says Roke. "We have developed a unique apparatus that can distinctly measure the interfacial structure of a layer on the sub-nanometer length scale that surrounds a droplet of oil in water. Thus, we can 'see' what is on the interface, and do not have to deduce it from comparing bulk properties, which is far less accurate."

Disproving a hypothesis isn't enough to explain a phenomenon, however. Roke is studying a promising avenue, that explores the intrinsic quantum nature of the water molecule itself, which might be responsible for the phenomenon. "The measurements we've made as part of this refutation could be used to try and prove this explanation," she says. "It's fascinating, because quantum effects (the smallest of the smallest) might be responsible for macroscopic charging effects that influence so many properties that relate to the functioning of the human body."

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The above story is reprinted from materials provided by Ecole Polytechnique F?d?rale de Lausanne, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Kailash C. Jena, R?diger Scheu, Sylvie Roke. Surface Impurities Are Not Responsible For the Charge on the Oil/Water Interface: A Comment. Angewandte Chemie International Edition, 2012; DOI: 10.1002/anie.201204662

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/4sUdXJpBTXU/121127130250.htm

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San Diego Real Estate Insulated from New ... - CT Homes LLC

While some parts of the country continue to be hard hit by the foreclosure crisis San Diego real estate appears to have gained immunity.

Some states have seen incredibly high double digit surges in foreclosures in the last few months. This is now being compounded even further as September figures reveal a 25% leap in re-defaults on homes with loan modifications, and some types of loans continue to experience a 40% re-default rate within 12 months of loan modification, dragging out the foreclosure crisis even longer.

However, San Diego real estate seems to be protected from these negative trends and is actually heading in the opposite direction.

U-T San Diego reporting on the latest data reveals Notices of Default in San Diego County are now at an incredible 6 year low, dropping 9% from September to October 2012 and down 50% since last year.

This is even more significant since mortgage defaults typically rise at this time of year. Some want the public to believe this is a result of Obama policies finally kicking in, while others contend that San Diego has simply worked through the majority of troubled loans and potential foreclosures.

Still there were almost 1,000 new Notices of Default or initial foreclosure filings in San Diego County last month and the high number of short sales on underwater homes are certainly helping to stem the flow of foreclosures. However, short sales could certainly potentially dry up as we enter 2013 as incentives for homeowners complete them vanish.

For now the bottom line is that there are still plenty of opportunities for San Diego real estate investors in what is undoubtedly one of the healthiest housing markets in the world right now, providing a great place to buy and invest for growth and security.

Source: http://www.cthomesllc.com/2012/11/san-diego-real-estate-insulated-from-new-foreclosure-surge/

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Monday, November 26, 2012

See How SAP Can Help Your Business Run Better - Business Insider

'; } } if (google_ads[0].bidtype == "CPC") { /* insert this snippet for each ad call */ google_adnum = google_adnum + google_ads.length; } document.write(s); return; } google_ad_client = 'pub-0604454314447934'; /* substitute your client_id (pub-#) */ // google_ad_channel = '1122334455667788'; google_ad_output = 'js'; google_max_num_ads = '5'; // google_ad_type = 'text_html'; // google_image_size = '728x90'; google_feedback = 'on'; google_skip = google_adnum; /* to skip for multiple units, insert this snippet for each ad call */ google_ad_channel = '1230120361'; /* our ad channel */ // -->

Source: http://www.businessinsider.com/see-how-sap-can-help-your-business-run-better-2012-11

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Bangladesh garment factory fire kills 120

DHAKA (Reuters) - A fire swept through a garment factory on the outskirts of Bangladesh's capital, killing at least 120 people, the chief of the fire brigade said on Sunday, in the worst accident for the booming industry in recent years.

The fire at the nine-story factory in the Ashulia industrial belt started on the ground floor late on Saturday and quickly spread, trapping hundreds of workers.

"This morning we have recovered 120 dead bodies and the death toll could rise," Abu Nayeem Mohammad Shahidullah, director general of the fire brigade, told reporters.

Bangladesh has around 4,500 garment factories that make clothes for brands including Tesco, Wal-Mart, JC Penney, H&M, Marks & Spencer, Kohl's and Carrefour.

Witnesses said the workers, mostly women, ran for safety as the fire engulfed the plant, but were unable to come out through narrow exits.

"Many jumped out from the windows and were injured, or died on the spot," Milon, a resident, said

The fire leapt high into the sky and could be seen from miles (kms) away.

Bangladesh is the world's biggest exporter of clothing after China, with garments making up 80 percent of its $24 billion annual exports.

But safety standards at the factories are poor and not enforced strictly, causing scores of accidents each year.

"We are appalled to see the charred bodies coming out of the factory since last night. It was an endless stream," Milon said.

Saturday's fire was the worst in years and rescuers and police said the death count may surpass any previous toll.

Earlier this year, more than 300 factories near the capital were shut for almost a week as workers demanded higher wages and better working conditions.

(Reporting by Ruma Paul and Anis Ahmed; Editing by Sanjeev Miglani)

Source: http://news.yahoo.com/bangladesh-garment-factory-fire-kills-120-042747909.html

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Sunday, November 25, 2012

ScienceDaily: Gene News

ScienceDaily: Gene Newshttp://www.sciencedaily.com/news/health_medicine/genes/ Genes and Genetics News. Read today's medical research in genetics including what can damage genes, what can protect them, and more.en-usSat, 24 Nov 2012 19:22:38 ESTSat, 24 Nov 2012 19:22:38 EST60ScienceDaily: Gene Newshttp://www.sciencedaily.com/images/logosmall.gifhttp://www.sciencedaily.com/news/health_medicine/genes/ For more science articles, visit ScienceDaily.New molecular culprit linked to breast cancer progressionhttp://www.sciencedaily.com/releases/2012/11/121124090511.htm Researchers have uncovered a protein ?partner? commonly used by breast cancer cells to unlock genes needed for spreading the disease around the body. A report on the discovery details how some tumors get the tools they need to metastasize.Sat, 24 Nov 2012 09:05:05 ESThttp://www.sciencedaily.com/releases/2012/11/121124090511.htmNew insights into virus proteome: Unknown proteins of the herpesvirus discoveredhttp://www.sciencedaily.com/releases/2012/11/121123092132.htm The genome encodes the complete information needed by an organism, including that required for protein production. Viruses, which are up to a thousand times smaller than human cells, have considerably smaller genomes. Using a type of herpesvirus as a model system scientists have shown that the genome of this virus contains much more information than previously assumed. The researchers identified several hundred novel proteins, many of which were surprisingly small.Fri, 23 Nov 2012 09:21:21 ESThttp://www.sciencedaily.com/releases/2012/11/121123092132.htmScientists describe elusive replication machinery of flu viruseshttp://www.sciencedaily.com/releases/2012/11/121122152928.htm Scientists have made a major advance in understanding how flu viruses replicate within infected cells. The researchers used cutting-edge molecular biology and electron-microscopy techniques to ?see? one of influenza?s essential protein complexes in unprecedented detail. The images generated in the study show flu virus proteins in the act of self-replication, highlighting the virus?s vulnerabilities that are sure to be of interest to drug developers.Thu, 22 Nov 2012 15:29:29 ESThttp://www.sciencedaily.com/releases/2012/11/121122152928.htmProtein folding: Look back on scientific advances made as result of 50-year old puzzlehttp://www.sciencedaily.com/releases/2012/11/121122152910.htm Fifty years after scientists first posed a question about protein folding, the search for answers has led to the creation of a full-fledged field of research that led to major advances in supercomputers, new materials and drug discovery, and shaped our understanding of the basic processes of life, including so-called "protein-folding diseases" such as Alzheimer's, Parkinson's and type II diabetes.Thu, 22 Nov 2012 15:29:29 ESThttp://www.sciencedaily.com/releases/2012/11/121122152910.htmStep forward in regenerating and repairing damaged nerve cellshttp://www.sciencedaily.com/releases/2012/11/121121145638.htm Researchers recently uncovered a nerve cell's internal clock, used during embryonic development. This breakthrough could lead to the development of new tools to repair and regenerate nerve cells following injuries to the central nervous system.Wed, 21 Nov 2012 14:56:56 ESThttp://www.sciencedaily.com/releases/2012/11/121121145638.htmArchitecture of rod sensory cilium disrupted by mutationhttp://www.sciencedaily.com/releases/2012/11/121121145621.htm Using a new technique called cryo-electron tomography, scientists have created a three-dimensional map that gives a better understanding of how the architecture of the rod sensory cilium (part of one type of photoreceptor in the eye) is changed by genetic mutation and how that affects its ability to transport proteins as part of the light-sensing process.Wed, 21 Nov 2012 14:56:56 ESThttp://www.sciencedaily.com/releases/2012/11/121121145621.htmAging: Scientists further unravel telomere biologyhttp://www.sciencedaily.com/releases/2012/11/121121130933.htm Researchers have resolved the structure of that allows a telomere-related protein, Cdc13, to form dimers in yeast. Mutations in this region of Cdc13 put the kibosh on the ability of telomerase and other proteins to maintain telomeres.Wed, 21 Nov 2012 13:09:09 ESThttp://www.sciencedaily.com/releases/2012/11/121121130933.htmDrug resistance biomarker could improve cancer treatmenthttp://www.sciencedaily.com/releases/2012/11/121121130811.htm Cancer therapies often have short-lived benefits due to the emergence of genetic mutations that cause drug resistance. A key gene that determines resistance to a range of cancer drugs has been reported in a new study. The study reveals a biomarker that can predict responses to cancer drugs and offers a strategy to treat drug-resistant tumors based on their genetic signature.Wed, 21 Nov 2012 13:08:08 ESThttp://www.sciencedaily.com/releases/2012/11/121121130811.htmGenome packaging: Key to breast cancer developementhttp://www.sciencedaily.com/releases/2012/11/121121130703.htm Two recent studies delve into the role of chromatin modifying enzymes and transcription factors in tumour cells. In one, it was found that the PARP1 enzyme activated by kinase CDK2 is necessary to induce the genes responsible for the proliferation of breast cancer cells in response to progesterone. In another, extensive work has been undertaken to identify those genes activated by the administration of progesterone in breast cancer, the sequences that can be recognized and how these genes are induced.Wed, 21 Nov 2012 13:07:07 ESThttp://www.sciencedaily.com/releases/2012/11/121121130703.htmShort DNA strands in genome may be key to understanding human cognition and diseaseshttp://www.sciencedaily.com/releases/2012/11/121121130643.htm Previously discarded, human-specific ?junk? DNA represents untapped resource in the study of diseases like Alzheimer?s and autism.Wed, 21 Nov 2012 13:06:06 ESThttp://www.sciencedaily.com/releases/2012/11/121121130643.htmBiomarking time: Methylome modifications offer new measure of our 'biological' agehttp://www.sciencedaily.com/releases/2012/11/121121130633.htm In a new study, researchers describe markers and a model that quantify how aging occurs at the level of genes and molecules, providing not just a more precise way to determine how old someone is, but also perhaps anticipate or treat ailments and diseases that come with the passage of time.Wed, 21 Nov 2012 13:06:06 ESThttp://www.sciencedaily.com/releases/2012/11/121121130633.htmKidney tumors have a mind of their ownhttp://www.sciencedaily.com/releases/2012/11/121121104552.htm New research has found there are several different ways that kidney tumors can achieve the same result -- namely, grow.Wed, 21 Nov 2012 10:45:45 ESThttp://www.sciencedaily.com/releases/2012/11/121121104552.htmMechanism to repair clumped proteins explainedhttp://www.sciencedaily.com/releases/2012/11/121121104416.htm Clumped proteins can be dissolved with the aid of cellular repair systems -- a process of critical importance for cell survival especially under conditions of stress. Researchers have now decrypted the fundamental mechanism for dissolving protein aggregates that involves specific molecular chaperones.Wed, 21 Nov 2012 10:44:44 ESThttp://www.sciencedaily.com/releases/2012/11/121121104416.htmNovel mechanism through which normal stromal cells become cancer-promoting stromal cells identifiedhttp://www.sciencedaily.com/releases/2012/11/121121104401.htm New understanding of molecular changes that convert harmless cells surrounding ovarian cancer cells into cells that promote tumor growth and metastasis provides potential new therapeutic targets for this deadly disease, according to new research.Wed, 21 Nov 2012 10:44:44 ESThttp://www.sciencedaily.com/releases/2012/11/121121104401.htmNew test for tuberculosis could improve treatment, prevent deaths in Southern Africahttp://www.sciencedaily.com/releases/2012/11/121120194932.htm A new rapid test for tuberculosis (TB) could substantially and cost-effectively reduce TB deaths and improve treatment in southern Africa -- a region where both HIV and tuberculosis are common.Tue, 20 Nov 2012 19:49:49 ESThttp://www.sciencedaily.com/releases/2012/11/121120194932.htmEvolution of human intellect: Human-specific regulation of neuronal geneshttp://www.sciencedaily.com/releases/2012/11/121120194926.htm A new study has identified hundreds of small regions of the genome that appear to be uniquely regulated in human neurons. These regulatory differences distinguish us from other primates, including monkeys and apes, and as neurons are at the core of our unique cognitive abilities, these features may ultimately hold the key to our intellectual prowess (and also to our potential vulnerability to a wide range of 'human-specific' diseases from autism to Alzheimer's).Tue, 20 Nov 2012 19:49:49 ESThttp://www.sciencedaily.com/releases/2012/11/121120194926.htmRibosome regulates viral protein synthesis, revealing potential therapeutic targethttp://www.sciencedaily.com/releases/2012/11/121120132906.htm Rather than target RNA viruses directly, aiming at the host cells they invade could hold promise, but any such strategy would have to be harmless to the host. Now, a surprising discovery made in ribosomes may point the way to fighting fatal viral infections such as rabies.Tue, 20 Nov 2012 13:29:29 ESThttp://www.sciencedaily.com/releases/2012/11/121120132906.htmHow does antibiotic resistance spread? Scientists find answers in the nosehttp://www.sciencedaily.com/releases/2012/11/121120121835.htm Microbiologists studying bacterial colonization in mice have discovered how the very rapid and efficient spread of antibiotic resistance works in the respiratory pathogen, Streptococcus pneumoniae (also known as the pneumococcus). The team found that resistance stems from the transfer of DNA between bacterial strains in biofilms in the nasopharynx, the area just behind the nose.Tue, 20 Nov 2012 12:18:18 ESThttp://www.sciencedaily.com/releases/2012/11/121120121835.htmScientists identify inhibitor of myelin formation in central nervous systemhttp://www.sciencedaily.com/releases/2012/11/121120100155.htm Scientists have discovered another molecule that plays an important role in regulating myelin formation in the central nervous system. Myelin promotes the conduction of nerve cell impulses by forming a sheath around their projections, the so-called axons, at specific locations -- acting like the plastic insulation around a power cord.Tue, 20 Nov 2012 10:01:01 ESThttp://www.sciencedaily.com/releases/2012/11/121120100155.htm'Obese but happy gene' challenges the common perception of link between depression and obesityhttp://www.sciencedaily.com/releases/2012/11/121120084725.htm Researchers have discovered new genetic evidence about why some people are happier than others. The scientists have uncovered evidence that the gene FTO -- the major genetic contributor to obesity -- is associated with an eight per cent reduction in the risk of depression. In other words, it's not just an obesity gene but a "happy gene" as well.Tue, 20 Nov 2012 08:47:47 ESThttp://www.sciencedaily.com/releases/2012/11/121120084725.htmTelomere lengths predict life expectancy in the wild, research showshttp://www.sciencedaily.com/releases/2012/11/121119213144.htm Researchers have found that biological age and life expectancy can be predicted by measuring an individual's DNA. They studied the length of chromosome caps -- known as telomeres -- in a 320-strong wild population of Seychelles Warblers on a small isolated island.Mon, 19 Nov 2012 21:31:31 ESThttp://www.sciencedaily.com/releases/2012/11/121119213144.htmCancer: Some cells don't know when to stophttp://www.sciencedaily.com/releases/2012/11/121119171403.htm Certain mutated cells keep trying to replicate their DNA -- with disastrous results -- even after medications rob them of the raw materials to do so, according to new research.Mon, 19 Nov 2012 17:14:14 ESThttp://www.sciencedaily.com/releases/2012/11/121119171403.htmMultiple sclerosis ?immune exchange? between brain and blood is uncoveredhttp://www.sciencedaily.com/releases/2012/11/121119163301.htm DNA sequences obtained from a handful of patients with multiple sclerosis have revealed the existence of an ?immune exchange? that allows the disease-causing cells to move in and out of the brain.Mon, 19 Nov 2012 16:33:33 ESThttp://www.sciencedaily.com/releases/2012/11/121119163301.htmFruit fly studies guide investigators to molecular mechanism frequently misregulated in human cancershttp://www.sciencedaily.com/releases/2012/11/121119132056.htm Changes in how DNA interacts with histones ?- the proteins that package DNA ?- regulate many fundamental cell activities from stem cells maturing into a specific body cell type or blood cells becoming leukemic. These interactions are governed by a biochemical tug of war between repressors and activators, which chemically modify histones signaling them to clamp down tighter on DNA or move aside and allow a gene to be expressed.Mon, 19 Nov 2012 13:20:20 ESThttp://www.sciencedaily.com/releases/2012/11/121119132056.htm3-D light switch for the brain: Device may help treat Parkinson's, epilepsy; aid understanding of consciousnesshttp://www.sciencedaily.com/releases/2012/11/121119114249.htm A new tool for neuroscientists delivers a thousand pinpricks of light to individual neurons in the brain. The new 3-D "light switch", created by biologists and engineers, could one day be used as a neural prosthesis that could treat conditions such as Parkinson's and epilepsy by using gene therapy to turn individual brain cells on and off with light.Mon, 19 Nov 2012 11:42:42 ESThttp://www.sciencedaily.com/releases/2012/11/121119114249.htmNew factor of genetic susceptibility to Alzheimer's diseasehttp://www.sciencedaily.com/releases/2012/11/121119104944.htm A large-scale international study has just discovered a gene for susceptibility to a rare disease providing evidence of the heterogeneous aetiology of Alzheimer's disease.Mon, 19 Nov 2012 10:49:49 ESThttp://www.sciencedaily.com/releases/2012/11/121119104944.htmBlood cancer gene BCL6 identified as a key factor for differentiation of nerve cells of cerebral cortexhttp://www.sciencedaily.com/releases/2012/11/121119093848.htm The cerebral cortex is the most complex structure in our brain and the seat of consciousness, emotion, motor control and language. In order to fulfill these functions, it is composed of a diverse array of nerve cells, called cortical neurons, which are affected by many neurological and neuropsychiatric diseases. Researchers have opened new perspectives on brain development and stem cell neurobiology by discovering a gene called BCL6 as a key factor in the generation of cortical neurons during embryonic brain development.Mon, 19 Nov 2012 09:38:38 ESThttp://www.sciencedaily.com/releases/2012/11/121119093848.htmMinority report: Insight into subtle genomic differences among our own cellshttp://www.sciencedaily.com/releases/2012/11/121118141530.htm Scientists have demonstrated that induced pluripotent stem cells -- the embryonic-stem-cell look-alikes whose discovery a few years ago won this year's Nobel Prize in medicine -- are not as genetically unstable as was thought.Sun, 18 Nov 2012 14:15:15 ESThttp://www.sciencedaily.com/releases/2012/11/121118141530.htmSkin cells reveal DNA's genetic mosaichttp://www.sciencedaily.com/releases/2012/11/121118141524.htm The prevailing wisdom has been that every cell in the body contains identical DNA. However, a new study of stem cells derived from the skin has found that genetic variations are widespread in the body's tissues, a finding with profound implications for genetic screening.Sun, 18 Nov 2012 14:15:15 ESThttp://www.sciencedaily.com/releases/2012/11/121118141524.htmLikely basis of birth defect causing premature skull closure in infants identifiedhttp://www.sciencedaily.com/releases/2012/11/121118141432.htm Geneticists, pediatricians, surgeons and epidemiologists have identified two areas of the human genome associated with the most common form of non-syndromic craniosynostosis premature closure of the bony plates of the skull.Sun, 18 Nov 2012 14:14:14 ESThttp://www.sciencedaily.com/releases/2012/11/121118141432.htmDNA packaging discovery reveals principles by which CRC mutations may cause cancerhttp://www.sciencedaily.com/releases/2012/11/121117184658.htm A new discovery concerning a fundamental understanding about how DNA works will produce a "180-degree change in focus" for researchers who study how gene packaging regulates gene activity, including genes that cause cancer and other diseases.Sat, 17 Nov 2012 18:46:46 ESThttp://www.sciencedaily.com/releases/2012/11/121117184658.htmHepatitis C treatment's side effects can now be studied in the labhttp://www.sciencedaily.com/releases/2012/11/121116161059.htm Adverse side effects of certain hepatitis C medications can now be replicated in the lab, thanks to a research team. The new method aids understanding of recent failures of hepatitis C antiviral drugs in some patients, and could help to identify medications that eliminate adverse effects. The findings may aid the development of safer and more effective treatments for hepatitis C and other pathogens such as SARS and West Nile virus.Fri, 16 Nov 2012 16:10:10 ESThttp://www.sciencedaily.com/releases/2012/11/121116161059.htmReconsidering cancer's bad guyhttp://www.sciencedaily.com/releases/2012/11/121116124644.htm Researchers have found that a protein, known for causing cancer cells to spread around the body, is also one of the molecules that trigger repair processes in the brain.Fri, 16 Nov 2012 12:46:46 ESThttp://www.sciencedaily.com/releases/2012/11/121116124644.htmGene distinguishes early birds from night owls and helps predict time of deathhttp://www.sciencedaily.com/releases/2012/11/121116124551.htm New research shows that a gene is responsible for a person's tendency to be an early riser or night owl -- and helps determine the time of day a person is most likely to die.Fri, 16 Nov 2012 12:45:45 ESThttp://www.sciencedaily.com/releases/2012/11/121116124551.htmClues to cause of kids' brain tumorshttp://www.sciencedaily.com/releases/2012/11/121116091226.htm Insights from a genetic condition that causes brain cancer are helping scientists better understand the most common type of brain tumor in children.Fri, 16 Nov 2012 09:12:12 ESThttp://www.sciencedaily.com/releases/2012/11/121116091226.htmArthritis study reveals why gender bias is all in the geneshttp://www.sciencedaily.com/releases/2012/11/121115210541.htm Researchers have pieced together new genetic clues to the arthritis puzzle in a study that brings potential treatments closer to reality and could also provide insights into why more women than men succumb to the disabling condition.Thu, 15 Nov 2012 21:05:05 ESThttp://www.sciencedaily.com/releases/2012/11/121115210541.htmClass of RNA molecules protects germ cells from damagehttp://www.sciencedaily.com/releases/2012/11/121115172255.htm Passing one's genes on to the next generation is a mark of evolutionary success. So it makes sense that the body would work to ensure that the genes the next generation inherits are exact replicas of the originals. Biologists have now identified one way the body does exactly that.Thu, 15 Nov 2012 17:22:22 ESThttp://www.sciencedaily.com/releases/2012/11/121115172255.htmQuick test speeds search for Alzheimer's drugs: Compound restores motor function and longevity to fruit flieshttp://www.sciencedaily.com/releases/2012/11/121115152655.htm Researchers report that an efficient, high-volume technique for testing potential drug treatments for Alzheimer's disease uncovered an organic compound that restored motor function and longevity to fruit flies with the disease.Thu, 15 Nov 2012 15:26:26 ESThttp://www.sciencedaily.com/releases/2012/11/121115152655.htmProtein-making machinery can switch gears with a small structural change process; Implications for immunity and cancer therapyhttp://www.sciencedaily.com/releases/2012/11/121115133414.htm For the past several years, research has focused on the intricate actions of an ancient family of catalytic enzymes that play a key role in translation, the process of producing proteins. In a new study, scientists have shown that this enzyme can actually also work in another fundamental process in humans.Thu, 15 Nov 2012 13:34:34 ESThttp://www.sciencedaily.com/releases/2012/11/121115133414.htmPlant derivative, tanshinones, protects against sepsis, study suggestshttp://www.sciencedaily.com/releases/2012/11/121115133312.htm Researchers have discovered that tanshinones, which come from the plant Danshen and are highly valued in Chinese traditional medicine, protect against the life-threatening condition sepsis.Thu, 15 Nov 2012 13:33:33 ESThttp://www.sciencedaily.com/releases/2012/11/121115133312.htmStructure of enzyme topoisomerase II alpha unravelled providing basis for more accurate design of chemotherapeutic drugshttp://www.sciencedaily.com/releases/2012/11/121115132903.htm Medical researchers have for the first time described the structure of the active site core of topoisomerase II alpha, an important target for anti-cancer drugs. The type II topoisomerases are important enzymes that are involved in maintaining the structure of DNA and chromosome segregation during both replication and transcription of DNA. One of these enzymes, topoisomerase II alpha, is involved in the replication of DNA and cell proliferation, and is highly expressed in rapidly dividing cancer cells.Thu, 15 Nov 2012 13:29:29 ESThttp://www.sciencedaily.com/releases/2012/11/121115132903.htmNewly discovered enzyme important in the spreading of cancerhttp://www.sciencedaily.com/releases/2012/11/121115132901.htm Enzyme hunters at UiO have discovered the function of an enzyme that is important in the spreading of cancer. Cancer researchers now hope to inhibit the enzyme.Thu, 15 Nov 2012 13:29:29 ESThttp://www.sciencedaily.com/releases/2012/11/121115132901.htmGenetics point to serious pregnancy complication, pre-eclampsiahttp://www.sciencedaily.com/releases/2012/11/121115132613.htm New research has revealed a genetic link in pregnant moms - and their male partners - to pre-eclampsia, a life-threatening complication during pregnancy.Thu, 15 Nov 2012 13:26:26 ESThttp://www.sciencedaily.com/releases/2012/11/121115132613.htmMolecular mechanisms underlying stem cell reprogramming decodedhttp://www.sciencedaily.com/releases/2012/11/121115132344.htm Thanks to some careful detective work, scientist better understand just how iPS cells form ? and why the Yamanaka process is inefficient, an important step to work out for regenerative medicine. The findings uncover cellular impediments to iPS cell development that, if overcome, could dramatically improve the efficiency and speed of iPS cell generation.Thu, 15 Nov 2012 13:23:23 ESThttp://www.sciencedaily.com/releases/2012/11/121115132344.htmSurprising genetic link between kidney defects and neurodevelopmental disorders in kidshttp://www.sciencedaily.com/releases/2012/11/121115132342.htm About 10 percent of kids born with kidney defects have large alterations in their genomes known to be linked with neurodevelopmental delay and mental illness, a new study has shown.Thu, 15 Nov 2012 13:23:23 ESThttp://www.sciencedaily.com/releases/2012/11/121115132342.htmEven moderate drinking in pregnancy can affect a child's IQhttp://www.sciencedaily.com/releases/2012/11/121114172833.htm Relatively small levels of exposure to alcohol while in the womb can influence a child's IQ, according to a new study using data from over 4,000 mothers and their children.Wed, 14 Nov 2012 17:28:28 ESThttp://www.sciencedaily.com/releases/2012/11/121114172833.htmGene nearly triples risk of Alzheimer's, international research team findshttp://www.sciencedaily.com/releases/2012/11/121114171710.htm A gene so powerful it nearly triples the risk of Alzheimer's disease has been discovered by an international team of researchers. It is the most potent genetic risk factor for Alzheimer's identified in the past 20 years.Wed, 14 Nov 2012 17:17:17 ESThttp://www.sciencedaily.com/releases/2012/11/121114171710.htmDiscovery could lead to faster diagnosis for some chronic fatigue syndrome caseshttp://www.sciencedaily.com/releases/2012/11/121114171708.htm For the first time, researchers have landed on a potential diagnostic method to identify at least a subset of patients with chronic fatigue syndrome - testing for antibodies linked to latent Epstein-Barr virus reactivation.Wed, 14 Nov 2012 17:17:17 ESThttp://www.sciencedaily.com/releases/2012/11/121114171708.htmResearch breakthrough could halt melanoma metastasis, study suggestshttp://www.sciencedaily.com/releases/2012/11/121114153227.htm In laboratory experiments, scientists have eliminated metastasis, the spread of cancer from the original tumor to other parts of the body, in melanoma by inhibiting a protein known as melanoma differentiation associated gene-9 (mda-9)/syntenin.Wed, 14 Nov 2012 15:32:32 ESThttp://www.sciencedaily.com/releases/2012/11/121114153227.htmPig genomes provide massive amount of genomic data for human healthhttp://www.sciencedaily.com/releases/2012/11/121114134512.htm Researchers provide a whole-genome sequence and analysis of number of pig breeds, including a miniature pig that serves a model for human medical studies and therapeutic drug testing.Wed, 14 Nov 2012 13:45:45 ESThttp://www.sciencedaily.com/releases/2012/11/121114134512.htmRare parasitic fungi could have anti-flammatory benefitshttp://www.sciencedaily.com/releases/2012/11/121114134054.htm Caterpillar fungi are rare parasites found on hibernating caterpillars in the mountains of Tibet. For centuries they have been highly prized as a traditional Chinese medicine - just a small amount can fetch hundreds of dollars.Wed, 14 Nov 2012 13:40:40 ESThttp://www.sciencedaily.com/releases/2012/11/121114134054.htmCancer therapy: Nanokey opens tumors to attackhttp://www.sciencedaily.com/releases/2012/11/121114113803.htm There are plenty of effective anticancer agents around. The problem is that, very often, they cannot gain access to all the cells in solid tumors. A new gene delivery vehicle may provide a way of making tracks to the heart of the target.Wed, 14 Nov 2012 11:38:38 ESThttp://www.sciencedaily.com/releases/2012/11/121114113803.htmHigh sperm DNA damage a leading cause of 'unexplained infertility', research findshttp://www.sciencedaily.com/releases/2012/11/121114113235.htm New research has uncovered the cause of infertility for 80 per cent of couples previously diagnosed with 'unexplained infertility': high sperm DNA damage.Wed, 14 Nov 2012 11:32:32 ESThttp://www.sciencedaily.com/releases/2012/11/121114113235.htmA risk gene for cannabis psychosishttp://www.sciencedaily.com/releases/2012/11/121114083928.htm The ability of cannabis to produce psychosis has long been an important public health concern. This concern is growing in importance as there is emerging data that cannabis exposure during adolescence may increase the risk of developing schizophrenia, a serious psychotic disorder. Further, with the advent of medical marijuana, a new group of people with uncertain psychosis risk may be exposed to cannabis.Wed, 14 Nov 2012 08:39:39 ESThttp://www.sciencedaily.com/releases/2012/11/121114083928.htmBacterial DNA sequence used to map an infection outbreakhttp://www.sciencedaily.com/releases/2012/11/121113214635.htm For the first time, researchers have used DNA sequencing to help bring an infectious disease outbreak in a hospital to a close. Researchers used advanced DNA sequencing technologies to confirm the presence of an ongoing outbreak of methicillin-resistant Staphylococcus aureus (MRSA) in a Special Care Baby Unit in real time. This assisted in stopping the outbreak earlier, saving possible harm to patients. This approach is much more accurate than current methods used to detect hospital outbreaks.Tue, 13 Nov 2012 21:46:46 ESThttp://www.sciencedaily.com/releases/2012/11/121113214635.htmGenetic variation may modify associations between low vitamin D levels and adverse health outcomeshttp://www.sciencedaily.com/releases/2012/11/121113161506.htm Findings from a study suggest that certain variations in vitamin D metabolism genes may modify the association of low serum 25-hydroxyvitamin D concentrations with health outcomes such as hip fracture, heart attack, cancer, and death.Tue, 13 Nov 2012 16:15:15 ESThttp://www.sciencedaily.com/releases/2012/11/121113161506.htmNew type of bacterial protection found within cells: Novel immune system response to infections discoveredhttp://www.sciencedaily.com/releases/2012/11/121113143656.htm Biologists have discovered that fats within cells store a class of proteins with potent antibacterial activity, revealing a previously unknown type of immune system response that targets and kills bacterial infections.Tue, 13 Nov 2012 14:36:36 ESThttp://www.sciencedaily.com/releases/2012/11/121113143656.htmGlutamate neurotransmission system may be involved with depression riskhttp://www.sciencedaily.com/releases/2012/11/121113134807.htm Researchers using a new approach to identifying genes associated with depression have found that variants in a group of genes involved in transmission of signals by the neurotransmitter glutamate appear to increase the risk of depression.Tue, 13 Nov 2012 13:48:48 ESThttp://www.sciencedaily.com/releases/2012/11/121113134807.htmTargeting downstream proteins in cancer-causing pathway shows promise in cell, animal modelhttp://www.sciencedaily.com/releases/2012/11/121113134230.htm The cancer-causing form of the gene Myc alters the metabolism of mitochondria, the cell?s powerhouse, making it dependent on the amino acid glutamine for survival. Depriving cells of glutamine selectively induces programmed cell death in cells overexpressing mutant Myc. Using Myc-active neuroblastoma cells, a team three priotein executors of the glutamine-starved cell, representing a downstream target at which to aim drugs. Roughly 25 percent of all neuroblastoma cases are associated with Myc-active cells.Tue, 13 Nov 2012 13:42:42 ESThttp://www.sciencedaily.com/releases/2012/11/121113134230.htmEven low-level radioactivity is damaging, scientists concludehttp://www.sciencedaily.com/releases/2012/11/121113134224.htm Even the very lowest levels of radiation are harmful to life, scientists have concluded, reporting the results of a wide-ranging analysis of 46 peer-reviewed studies published over the past 40 years. Variation in low-level, natural background radiation was found to have small, but highly statistically significant, negative effects on DNA as well as several measures of health.Tue, 13 Nov 2012 13:42:42 ESThttp://www.sciencedaily.com/releases/2012/11/121113134224.htm

Source: http://www.sciencedaily.com/rss/health_medicine/genes.xml

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